Isola, Mississippi has a Humid Subtropical Climate climate (Köppen classification: Cfa). Average annual temperatures range from 54.2 °F (low) to 74.4 °F (high). Annual precipitation averages 56.5 Inches. Isola is located in USDA Plant Hardiness Zone 8b. The growing season typically runs from the last frost around Mar. 11 - Mar. 20 through the first frost around Nov. 1 - Nov. 10.
| Month | Avg. Low | Avg. High | Avg. Precip |
|---|---|---|---|
| January | 35.5 °F | 53.2 °F | 5.4 in. |
| February | 38.5 °F | 57.7 °F | 5.25 in. |
| March | 45.7 °F | 66.2 °F | 5.28 in. |
| April | 54.0 °F | 74.9 °F | 6.15 in. |
| May | 63.2 °F | 82.9 °F | 5.19 in. |
| June | 70.1 °F | 89.0 °F | 3.76 in. |
| July | 72.6 °F | 91.3 °F | 4.31 in. |
| August | 71.3 °F | 91.8 °F | 3.45 in. |
| September | 65.0 °F | 87.6 °F | 3.44 in. |
| October | 53.7 °F | 77.5 °F | 3.95 in. |
| November | 43.6 °F | 65.1 °F | 4.58 in. |
| December | 37.6 °F | 55.8 °F | 5.7 in. |
| Annual | 54.2 °F | 74.4 °F | 56.46 in. |
| Average First Frost Date | Nov. 1 - Nov. 10 |
| Average Last Frost Date | Mar. 11 - Mar. 20 |
| Average Days With Frost | 40-50 Days |
| Plant Hardiness Zone | Zone 8b : 15°F to 20°F |
| Plant Hardiness Zone - 2012 | Zone 8a : 10°F to 15°F |
| Current Drought Conditions | Severe Drought |
| Köppen Climate Classification | Cfa - Humid Subtropical Climate |