Mayersville, Mississippi has a Humid Subtropical Climate climate (Köppen classification: Cfa). Average annual temperatures range from 54.3 °F (low) to 75 °F (high). Annual precipitation averages 57.9 Inches. Mayersville is located in USDA Plant Hardiness Zone 8b. The growing season typically runs from the last frost around Mar. 11 - Mar. 20 through the first frost around Nov. 11 - Nov. 20.
| Month | Avg. Low | Avg. High | Avg. Precip |
|---|---|---|---|
| January | 35.6 °F | 54.2 °F | 5.67 in. |
| February | 38.8 °F | 58.7 °F | 5.14 in. |
| March | 46.0 °F | 67.0 °F | 5.31 in. |
| April | 54.2 °F | 75.5 °F | 6.27 in. |
| May | 63.0 °F | 83.0 °F | 4.85 in. |
| June | 69.9 °F | 89.3 °F | 3.97 in. |
| July | 72.5 °F | 91.7 °F | 4.13 in. |
| August | 71.3 °F | 91.9 °F | 3.97 in. |
| September | 64.8 °F | 87.7 °F | 3.63 in. |
| October | 53.5 °F | 78.0 °F | 4.5 in. |
| November | 43.6 °F | 65.9 °F | 4.69 in. |
| December | 37.9 °F | 56.8 °F | 5.8 in. |
| Annual | 54.3 °F | 75 °F | 57.93 in. |
| Average First Frost Date | Nov. 11 - Nov. 20 |
| Average Last Frost Date | Mar. 11 - Mar. 20 |
| Average Days With Frost | 40-50 Days |
| Plant Hardiness Zone | Zone 8b : 15°F to 20°F |
| Plant Hardiness Zone - 2012 | Zone 8a : 10°F to 15°F |
| Current Drought Conditions | Moderate Drought |
| Köppen Climate Classification | Cfa - Humid Subtropical Climate |