Santee, South Carolina has a Humid Subtropical Climate climate (Köppen classification: Cfa). Average annual temperatures range from 53.6 °F (low) to 75.7 °F (high). Annual precipitation averages 49.2 Inches. Santee is located in USDA Plant Hardiness Zone 8b. The growing season typically runs from the last frost around Mar. 11 - Mar. 20 through the first frost around Nov. 11 - Nov. 20.
| Month | Avg. Low | Avg. High | Avg. Precip |
|---|---|---|---|
| January | 35.5 °F | 57.9 °F | 3.75 in. |
| February | 38.0 °F | 61.4 °F | 3.63 in. |
| March | 44.2 °F | 68.7 °F | 3.77 in. |
| April | 52.3 °F | 76.9 °F | 3.33 in. |
| May | 60.8 °F | 83.4 °F | 3.68 in. |
| June | 68.5 °F | 88.8 °F | 5.35 in. |
| July | 71.8 °F | 91.5 °F | 5.45 in. |
| August | 70.7 °F | 89.8 °F | 5.36 in. |
| September | 65.7 °F | 85.2 °F | 4.74 in. |
| October | 54.5 °F | 77.0 °F | 3.72 in. |
| November | 43.4 °F | 67.5 °F | 2.72 in. |
| December | 38.2 °F | 60.6 °F | 3.71 in. |
| Annual | 53.6 °F | 75.7 °F | 49.21 in. |
| Average First Frost Date | Nov. 11 - Nov. 20 |
| Average Last Frost Date | Mar. 11 - Mar. 20 |
| Average Days With Frost | 40-50 Days |
| Plant Hardiness Zone | Zone 8b : 15°F to 20°F |
| Plant Hardiness Zone - 2012 | Zone 8b : 15°F to 20°F |
| Current Drought Conditions | Severe Drought |
| Köppen Climate Classification | Cfa - Humid Subtropical Climate |